SEIR

From TheAnalogThing

In this example a simple SEIR-model of an infectious disease is setup. This is a classical model with four time varying variables representing the set of susceptible, exposed, infected, and recovered persons.

The model is described by four coupled differential equations, one for each of the four variables. Initially, all persons are susceptible in a simulation as they have not been exposed to the disease yet. The number of susceptible persons is computed by the topmost integrator in the program shown below. This integrator has an initial condition of -1 thus yielding S=+1 initially.

The parameter β basically represents the probability of a susceptible person meeting an infected person. (Social distancing would decrease β for example.) The first derivative of S with respect to time (denoted by a dot on top of the variable S) is thus -βSI.

A formerly susceptible person which has been exposed to an infected person is thus removed from the set of susceptible persons and becomes an exposed person E. So the time derivative of E has one term βSI increasing E. Exposed persons become infected persons at a rate determined by α yielding a second term to the time derivative of E.

Accordingly I is increased at the rate αE and decreased at the rate γI which represents recovered (or removed if they might have died) persons. The parameter I(0) represents the number of infected persons at the start of the simulation run.

The number of recovered/removed persons R is increased by γI accordingly.

SEIR program.pdf

The actual setup of this program on a THAT looks like this:

SEIR setup.jpg

β, α, γ, and I(0) are represented by the coefficient potentiometers 1, 2, 3, and 4 respectively.

A typical simulation result looks like this screenshot from a four-channel oscilloscope:

SEIR result 2 small.jpg

The trace starting at the upper left represents S. The three traces starting at the lower left a E, I, and R. The curve representing E is the one which bulges first, followed by I, while R steadily increases until all susceptible persons have been exposed, infected, and recovered (or removed).